Deborah C Mash Selected Research

noribogaine

1/2016	Oral noribogaine shows high brain uptake and anti-withdrawal effects not associated with place preference in rodents.
12/2015	Noribogaine is a G-protein biased κ-opioid receptor agonist.
6/2015	Noribogaine reduces nicotine self-administration in rats.

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Deborah C Mash Research Topics

Disease

18	Parkinson Disease (Parkinson's Disease) 01/2018 - 04/2003
14	Alzheimer Disease (Alzheimer's Disease) 09/2019 - 07/2002
9	Cocaine-Related Disorders (Cocaine Addiction) 10/2021 - 04/2003
9	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021 - 04/2005
7	Parkinsonian Disorders (Parkinsonism) 01/2020 - 02/2006
6	Dementia (Dementias) 01/2020 - 01/2009
5	Delirium 01/2016 - 04/2002
4	Alcoholism (Alcohol Abuse) 11/2019 - 07/2003
4	Multiple System Atrophy 01/2017 - 08/2007
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2020 - 10/2013
3	Substance-Related Disorders (Drug Abuse) 01/2016 - 06/2015
3	Cognitive Dysfunction 04/2014 - 10/2002
2	Opioid-Related Disorders (Opiate Addiction) 09/2021 - 01/2018
2	Sudden Death 01/2016 - 09/2009
2	Hyperthermia 01/2016 - 04/2003
2	Lewy Body Disease (Lewy Body Dementia) 01/2011 - 07/2009
2	Paranoid Disorders (Paranoia) 04/2003 - 04/2002
1	Infantile Parkinsonism-Dystonia 01/2022
1	Gliosis 01/2020
1	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2020
1	Autism Spectrum Disorder 01/2019
1	Late Onset Disorders 01/2018
1	Substance Withdrawal Syndrome (Withdrawal Symptoms) 01/2018
1	Neurodevelopmental Disorders 01/2017
1	Amyloid Plaque 01/2016
1	Mania (Manias) 01/2016
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2016
1	Tobacco Use Disorder (Nicotine Dependence) 06/2015
1	Hypothyroidism 03/2015
1	Inflammation (Inflammations) 03/2015
1	Mitochondrial Diseases (Mitochondrial Disease) 03/2015
1	Central Nervous System Diseases (CNS Diseases) 03/2015
1	Weight Loss (Weight Reduction) 02/2015
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 04/2014
1	Neuroinflammatory Diseases 04/2014
1	Synucleinopathies 01/2013
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 11/2012
1	Mental Disorders (Mental Disorder) 03/2011

Drug/Important Bio-Agent (IBA)

11	Cocaine (Cocaine HCl)IBA 10/2021 - 04/2002
11	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2003
7	alpha-SynucleinIBA 06/2015 - 04/2003
6	Dopamine (Intropin)FDA LinkGeneric 01/2017 - 11/2003
5	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2022 - 11/2003
5	Alanine (L-Alanine)FDA Link 10/2021 - 02/2015
4	Phosphotransferases (Kinase)IBA 01/2018 - 02/2006
4	Pharmaceutical PreparationsIBA 01/2018 - 06/2015
3	Ibogaine (Endabuse)IBA 09/2021 - 01/2016
3	noribogaineIBA 01/2016 - 06/2015
3	Biomarkers (Surrogate Marker)IBA 01/2016 - 09/2009
3	Apolipoproteins E (ApoE)IBA 11/2014 - 03/2007
3	Messenger RNA (mRNA)IBA 03/2011 - 11/2003
2	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 10/2021 - 11/2003
2	Dopamine Receptors (Dopamine Receptor)IBA 11/2019 - 03/2011
2	LipidsIBA 09/2019 - 01/2019
2	Serotonin (5 Hydroxytryptamine)IBA 01/2019 - 06/2015
2	Amyloid (Amyloid Fibrils)IBA 01/2019 - 05/2003
2	Opioid Analgesics (Opioids)IBA 01/2018 - 04/2008
2	Leucine (L-Leucine)FDA Link 01/2018 - 09/2006
2	Glucosylceramidase (Glucocerebrosidase)IBA 01/2018 - 01/2011
2	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2016 - 03/2013
2	Amino Acids FDA Link 10/2013 - 01/2009
2	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 03/2011 - 11/2003
1	5'- O- (4,4'- dimethoxytrityl)thymidine- 3'- O- (2,4- dinitrophenyl) succinate (DTDS)IBA 01/2022
1	hydrogen sulfite (bisulfite)IBA 01/2021
1	ChromatinIBA 01/2021
1	Protein AggregatesIBA 01/2020
1	Serine (L-Serine)FDA Link 01/2020
1	Carrier Proteins (Binding Protein)IBA 01/2019
1	Leucine-Rich Repeat Serine-Threonine Protein Kinase-2IBA 01/2018
1	HydrolasesIBA 01/2018
1	Narcotic Antagonists (Opioid Antagonists)IBA 01/2018
1	Biological ProductsIBA 01/2016
1	Dynorphins (Dynorphin)IBA 12/2015
1	CatecholaminesIBA 09/2015
1	Dihydroxyphenylalanine (Dopa)IBA 09/2015
1	Aldehyde DehydrogenaseIBA 06/2015
1	Opioid Receptors (Opioid Receptor)IBA 06/2015
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 06/2015
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 03/2015
1	UbiquitinIBA 03/2015
1	Iodide Peroxidase (Deiodinase)IBA 03/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2015
1	Free RadicalsIBA 02/2015
1	Thyrotropin-Releasing Hormone Receptors (Thyrotropin Releasing Hormone Receptor)IBA 02/2015
1	Neuroprotective AgentsIBA 02/2015
1	Kainic Acid (Kainate)IBA 02/2015
1	Threonine (L-Threonine)FDA Link 02/2015
1	ApolipoproteinsIBA 09/2014
1	Pattern Recognition ReceptorsIBA 04/2014
1	AntibodiesIBA 01/2013
1	Dihydrotachysterol (AT 10)IBA 01/2013
1	EpitopesIBA 01/2013
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 09/2012
1	EnzymesIBA 09/2012
1	gamma-Aminobutyric Acid (GABA)IBA 01/2012
1	MelatoninIBA 02/2010
1	MT2 Melatonin ReceptorIBA 02/2010
1	DNA (Deoxyribonucleic Acid)IBA 07/2009

Therapy/Procedure

2	Therapeutics 01/2018 - 11/2012
2	Denervation 01/2017 - 01/2017